DigeZyme®

A Versatile Multi-enzyme Complex

This proprietary preparation is a unique blend of specific digestive enzymes that offers much more than just aiding proper digestion and better absorption of nutrients.

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Rationale

Enzyme supplementation is highly recommended to get that ‘extra support’ to offset the accumulated negative impact of dietary errors

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Stability

1% solution of DigeZyme® was prepared in DM water and sugar syrup (50%, w/w) and subjected to 72 °C for 15 and 60 sec

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Safety

DigeZyme® gave a negative response in the presence and absence of Aroclor 1254-induced rat liver S9 in the assay up to 5000 µg/plate

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Clinical

In a 5-day pilot study, relative bioavailability of micronutrients like vitamin C and β-carotene in the presence of BioPerine® plus DigeZyme® or DigeZyme® alone was evaluated in healthy volunteers

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FAQs

It is a unique, proprietary blend of 5 specific enzymes, viz. α-amylase (starch hydrolyzing enzyme), protease (protein hydrolyzing enzyme), lipase (Fat hydrolyzing enzyme), cellulase (cellulose hydrolyzing enzyme), and lactase (lactose hydrolyzing enzyme).

Enzymes are the essential part of any chemical reaction that takes place in our body. Various biological reactions are regulated by different types of enzymes.

For example, several enzymes play a key role in the proper digestion of the food that we consume everyday in order to be assimilated and help body to absorb several nutrients.

Since ancient days, people have known the various health and nutritional benefits of enzymes. Today, people are convinced about enzymes’ role in improving overall health and wellness in general and gut/digestive health in particular—thanks to clinically-based evidence.

However, in some people, the body’s natural ability to produce certain pancreatic enzymes like lipase, amylase as well as other extra pancreatic enzymes that play a crucial role in macronutrient digestion starts declining very early (as early as 25 years of age). This might lead to malabsorption, if enzyme insufficiency is left unaddressed.

Supplementing with digestive enzymes takes care of your digestive health, while also supports weight management, joint health, relieving muscle soreness, and much more.

Enzyme supplementation helps:
To withstand the stress caused by sudden changes in food consumption patterns, exposure to environmental pollutants, extensive travel and unexpected changes in weather

In cases of enzyme insufficiency, caused by damage to the sites of enzyme production

To lessen the symptoms caused by digestive and metabolic disorders, wherein individuals lack specific enzymes. For example, lactose intolerance, which is caused by lactase deficiency

  • α–Amylase: Breaks down carbohydrates, such as starch, glycogen and polysaccharides into smaller units
  • Cellulase: Breaks down cellulose and chitin. It helps to free nutrients in both fruits and vegetables
  • Lipase: Breaks down lipids, improves fat utilization and supports healthy gallbladder function
  • Protease: Breaks down protein and peptides, supports immune function
  • Lactase: Breaks down lactose (milk sugar) and useful for lactose intolerance

A majority of the digestive enzyme supplements currently available in the market are from animal sources. Hence, enzyme origin would be a great concern for a customer who is strictly vegan. Microbial enzymes, often called “plant-derived,” are of bacterial or fungal origin and are produced through fermentation using these microorganisms.

Some of the best-known sources of microbial enzymes used in supplements include species like Aspergillus and Rhizopus (fungal), Bacillus (bacterial), and Saccharomyces (yeast).

Supplements having microbe-based enzymes are having several advantages: Activity of microbe-derived enzymes like lipase is believed to be similar to porcine and bovine pancreatic enzymes. Data on their safety and efficacy in the treatment of malabsorption and lactose intolerance are encouraging.

Another advantage is that they may be used at a lower dosage and possess a broader pH range of activity compared to animal-based enzymes. Another advantage of using micro-organisms as a source of enzymes for nutritional supplements is that they are inexpensive and provide abundant supply.

This microbe-based enzyme complex has the following salient features:

  • The ingredient is stable in a number of formulations
  • Each enzyme in this multi-enzyme complex formulation is of food grade and is non-GMO and gluten-free
  • The specifications of this product adhere to the most stringent international standards and regulatory norms, such as Food Chemicals Codex (FCC) representation, an accepted standard of the US FDA
  • All the enzymes used in this multi-enzyme complex are safe in terms of their origin, quality, and efficacy

DigeZyme® is safe and effective at a recommended daily dosage of 50 mg three times a day.

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Sabinsa’s Multi-Enzyme Complex DigeZyme® Demonstrated Efficacy in Management of Dyspeptic Symptoms with Functional Dyspepsia: Published Clinical Study
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